The European Commission announced the start of an "air bridge" operation to deliver an initial 50 tonnes of health supplies to Syria via neighbouring Turkey, AFP reported.
The products from the EU stockpile in Dubai will be transported to Adana, Turkey, for distribution in Syria "in the coming days", the Commission said in a statement.
Another 46 tonnes of humanitarian supplies will be transported by truck from an EU warehouse in Denmark to Adana, to be distributed in Syria by UNICEF and the World Health Organisation.
The UN humanitarian agency says more than a million people, mostly women and children, have been displaced in Syria since the rebel offensive that ousted President Bashar al-Assad began.
Commission chief Ursula von der Leyen said she would "continue to discuss the delivery of humanitarian aid" when she travels to Turkey to meet President Recep Tayyip Erdogan. Tayyip Erdogan on Tuesday.
"Given the extremely fragile situation on the ground, our assistance to the people of Syria is all the more important", she was quoted as saying.
The Commission said it had mobilised an additional €4 million "to address the most urgent humanitarian needs", bringing its total assistance for this year to €163 million ($170 million).
The new funding will cover costs for trauma kits, critical health supplies, emergency shelter kits and sanitary support, as well as facilitating the distribution of food packages to 61,500 people in northern Syria.
The UN World Food Programme has separately appealed for $250 million in food aid funding for Syria over the next six months to feed up to 2.8 million people. displaced and vulnerable people.
The fall of Assad ended a nearly 14-year war that killed more than 500,000 people and displaced millions.